News and Updates in Sarcoma Research

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New Research of Chondrosarcoma

A new study titled, “Lost miRNA surveillance of Notch, IGFR pathway — road to sarcomagenesis,” was published in the January issue of Tumor Biology. This study takes a look at pathways linked to the genesis of chondrosarcoma, cancer of the cells that produce cartilage.

Led by Karina Galoian, Ph.D., they compared and analyzed differentially expressed miRNA and their targets in chondrosarcoma versus control chondrocytes.

“Our study shows that lost miRNA surveillance of notch signaling and IGFR pathways is involved in and possibly leads to sarcomagenesis,” said Galoian. Click here to read comprehensive details of the study.

New Research on Cause of Kaposi’s sarcoma

There has been a new breakthrough in the studies of Kaposi’s sarcoma. UTSA, USC and UTHSCA researchers have discovered the causing factor in the virus responsible for Kaposi’s sarcoma.

The study was led by S.J. Gao, professor of microbiology and immunology at the Keck School of Medicine. Shou-Jiang Gao and his associates were able to distinguish the microRNA molecules that cause normal cells to become cancerous. Until recently, it was difficult to study the link between Kaposi’s sarcoma-associated herpesvirus and Kaposi’s sarcoma, because experimental cells that were infected with the virus died before they could become malignant cancer cells.

Click here to read the full article

Sarcoma Researcher Receives National Honor

Courtesy Forbes

Courtesy Forbes

And, Cigall Kadoch, an assistant pediatric oncology professor at Dana Farber was just honored. Forbes noted her work in studying how changes in the physical structure of cells can leas to synovial structure.

Not only is Kadoch doing outstanding research, but her placement in Forbes ’30 Under 30’ is helping raise awareness of sarcoma.

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